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Adrenal crisis (also known as Addisonian crisis and acute adrenal insufficiency) is a medical emergency and potentially life-threatening situation requiring immediate emergency treatment. It is a constellation of symptoms that indicate severe adrenal insufficiency caused by insufficient levels of the hormone cortisol. This may be the result of either previously undiagnosed or untreated Addison's disease, a disease process suddenly affecting adrenal function (such as bleeding from the adrenal glands in Waterhouse-Friderichsen syndrome), suddenly stopping intake of glucocorticoids, or an intercurrent problem (e.g. infection, trauma, in fact any form of physical or mental stress) in someone known to have Addison's disease or congenital adrenal hyperplasia (CAH). ==Signs and symptoms== Characteristic symptoms are:〔(【引用サイトリンク】 Addison's Disease )〕 * Sudden penetrating pain in the legs, lower back or abdomen * Confusion, psychosis, slurred speech * Severe lethargy * Convulsions * Fever * Hyperkalemia (elevated potassium level in the blood) * Hypercalcemia (elevated calcium level in the blood): the etiology of hypercalcemia is a combination of increased calcium input into the extracellular space and reduced calcium removal by the kidney, this last caused by decreased glomerular filtration and increased tubular calcium reabsorption. Both renal factors are secondary to volume depletion and, in fact, improve rapidly during rehydration with saline infusion.〔http://link.springer.com/article/10.1007%2FBF02411297〕 * Hypoglycemia (reduced level of blood glucose) * Hyponatremia (low sodium level in the blood) * Hypotension (low blood pressure) * Hypothyroid (low T4 level) * Severe vomiting and diarrhea, resulting in dehydration * Syncope (loss of consciousness and ability to stand) 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Adrenal crisis」の詳細全文を読む スポンサード リンク
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